Reishi mushroom: What is it, benefits, and side effects

Reishi mushrooms are becoming increasingly common in wellness routines, and it’s easy to see why. Renowned for their health benefits, these “super mushrooms” have been celebrated for centuries as natural healers. In this article, we’ll explore what reishi mushroom is, the science-backed benefits it offers, potential side effects, and how you can incorporate it into your wellness routine.

What is reishi mushroom?

Reishi mushroom, also known as Ganoderma lucidum or hongo reishi in Spanish, is a type of fungus that has been used in traditional medicine for centuries. In ancient cultures, it was known as the “mushroom of immortality” and is highly valued for its potential health benefits.

Reishi mushrooms grow naturally on hardwood trees, particularly in humid, temperate regions. Red reishi is the most commonly used variety due to its concentrated bioactive compounds.

Reishi benefits

Reishi mushroom offers a wide range of health benefits that make it a prized ingredient in traditional medicine and modern wellness routines. Let's explore its key benefits.

Boosts the immune system

Reishi mushrooms contain beta-glucans, which can improve the body’s immune response. They stimulate white blood cells to fight infections and harmful bacteria [1]. Studies suggest that consuming reishi extract can help balance the immune system, either by boosting it during illness or calming it when overactive [2].

Exhibits anticancer properties

Various reishi mushroom cancer studies suggest that this fungus may have properties that inhibit tumor growth. Its compounds, such as triterpenes, are believed to fight cancer cells while improving the efficacy of certain chemotherapy drugs [18]. Although not a cure, reishi health benefits in cancer prevention and management seem promising [3].

Reduces fatigue

People using reishi mushroom powder or reishi supplements often report feeling more energized. Studies support these claims by showing that reishi reduces stress and improves the body’s resilience to fatigue [4] [5]. Its adaptogenic properties make it particularly effective in managing chronic tiredness.

Lowers blood pressure and improves heart health

Triterpenes and antioxidants in reishi mushrooms can lower blood pressure and reduce cholesterol levels [7]. These compounds support overall cardiovascular health by improving blood circulation and reducing the risk of heart disease. Incorporating reishi tincture or reishi capsules into your routine could offer these heart-protective benefits.

Improves blood sugar

Reishi has been shown to regulate blood sugar levels by improving insulin sensitivity [8], which makes it beneficial for people with diabetes or those at risk. Regular consumption of reishi powder has been associated with better glycemic control and fewer complications linked to high blood sugar [9].

Reduces signs of aging

Reishi mushroom benefits for the skin include improved hydration, reduced wrinkles, and enhanced elasticity [10]. Antioxidants in reishi can help combat oxidative stress, which contributes to visible signs of aging [11]. A clinical study demonstrated that reishi extract when used in skincare products improved skin hydration and balanced skin pH [12].

Improves mood and depressive symptoms

Reishi’s adaptogenic properties extend to mental health, where it helps balance mood and reduce symptoms of anxiety and depression [13] [14]. Studies suggest that red reishi benefits those with stress-related disorders by calming the mind and promoting relaxation [15]. This ability to calm the mind and promote relaxation makes reishi a natural alternative for improving overall well-being.

Prevents inflammation and infection

Reishi mushrooms contain compounds that help reduce inflammation and fight infections [16]. Their anti-inflammatory properties are particularly useful for conditions like arthritis. Additionally, they have antimicrobial effects [17], helping protect the body from harmful bacteria and viruses.

Reishi mushroom side effects

While reishi health benefits are impressive, it is essential to be aware of potential reishi side effects. These may include dry mouth, upset stomach, and dizziness. People on blood-thinning medication or with low blood pressure should consult a doctor before using reishi supplements. Long-term use of reishi mushroom capsules or excessive doses may also cause adverse reactions.

Reishi extract forms

Reishi extract is available in various forms, including reishi tinctures, capsules, and powders. These products provide concentrated doses of the mushroom’s beneficial compounds. Reishi mushroom capsules are a convenient option for daily use, while reishi powder can be added to beverages or meals for a nutritional boost.

Bottom line

Reishi mushrooms are a powerful natural remedy with a wide range of health benefits, from boosting the immune system to improving mood and skin health. While reishi health benefits are backed by science, it is essential to use them responsibly to avoid potential side effects. Incorporating reishi extract or other longevity supplements into your routine can be an effective way to support overall well-being.

FAQ

What does a reishi mushroom do for your body?

Reishi mushrooms support the immune system, improve energy levels, and promote overall health. They have anticancer properties, regulate blood sugar, and improve mental well-being. Additionally, their antioxidant properties help protect against aging and inflammation.

Can reishi mushrooms be consumed directly in their natural form?

Reishi mushrooms are not commonly consumed as food because of their tough texture and bitter taste. Instead, they are primarily used in powdered, capsuled, or liquid forms. 

Is reishi mushroom a psychedelic?

No, reishi mushrooms are not psychedelic. Unlike mushrooms containing psilocybin, reishi does not cause hallucinations or alter perception.

Who should not take reishi mushrooms?

People with low blood pressure, bleeding disorders, or those on blood-thinning medications should avoid reishi. Pregnant or breastfeeding individuals should consult a healthcare provider before using reishi supplements.

How long does it take for reishi mushrooms to work?

The effects of reishi mushrooms can vary depending on the individual and the form of consumption. Most people report noticeable benefits—such as reduced fatigue, decreased anxiety, and improved overall well-being—after four to eight weeks of consistent use [4] [6].

References

[1] Saha, T. K., Mariom, Rahman, T., Moniruzzaman, M., Min, T., & Hossain, Z. (2023). Immuno-physiological effects of dietary reishi mushroom powder as a source of beta-glucan on Rohu, Labeo rohita challenged with Aeromonas veronii. Scientific reports, 13(1), 14652. https://doi.org/10.1038/s41598-023-41557-9 

[2] Mallard, B., Leach, D. N., Wohlmuth, H., & Tiralongo, J. (2019). Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake, and Maitake. PLOS ONE, 14(11), e0224740. https://doi.org/10.1371/journal.pone.0224740

[3] Jin, X., Ruiz Beguerie, J., Sze, D. M., & Chan, G. C. (2012). Ganoderma lucidum (Reishi mushroom) for cancer treatment. The Cochrane database of systematic reviews, (6), CD007731. https://doi.org/10.1002/14651858.CD007731.pub2 

[4] Zhao, H., Zhang, Q., Zhao, L., Huang, X., Wang, J., & Kang, X. (2012). Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evidence-Based Complementary and Alternative Medicine, 2012, 1–8. https://doi.org/10.1155/2012/809614 

[5] Li, X., Sun, L., Chimonas, S., Li, S. Q., Feng, P., Yang, Y., & Mao, J. J. (2024). Symptom improvements and adverse effects with Reishi mushroom use: A cross-sectional survey of cancer patients. Integrative Medicine Research, 13(4), 101089. https://doi.org/10.1016/j.imr.2024.101089 

[6] Tang, W., Gao, Y., Chen, G., Gao, H., Dai, X., Ye, J., Chan, E., Huang, M., & Zhou, S. (2005). A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia. Journal of medicinal food, 8(1), 53–58. https://doi.org/10.1089/jmf.2005.8.53 

[7] Klupp, N. L., Chang, D., Hawke, F., Kiat, H., Cao, H., Grant, S. J., & Bensoussan, A. (2015). Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. The Cochrane database of systematic reviews, 2015(2), CD007259. https://doi.org/10.1002/14651858.CD007259.pub2

[8] Wang, F., Zhou, Z., Ren, X. et al. Effect of Ganoderma lucidum spores intervention on glucose and lipid metabolism gene expression profiles in type 2 diabetic rats. Lipids Health Dis 14, 49 (2015). https://doi.org/10.1186/s12944-015-0045-y 

[9] Aramabašić Jovanović, J., Mihailović, M., Uskoković, A., Grdović, N., Dinić, S., & Vidaković, M. (2021). The Effects of Major Mushroom Bioactive Compounds on Mechanisms That Control Blood Glucose Level. Journal of Fungi, 7(1), 58. https://doi.org/10.3390/jof7010058 

[10] Rezaeian, S., & Pourianfar, H. (2023). A review of the effects of Reishi mushroom (Ganoderma lucidum) on skin health and diseases. JDC, 13(4), 274–284. http://jdc.tums.ac.ir/article-1-5632-en.html 

[11] Luo, J., Ganesan, K., & Xu, B. (2024). Unlocking the Power: New Insights into the Anti-Aging Properties of Mushrooms. Journal of fungi (Basel, Switzerland), 10(3), 215. https://doi.org/10.3390/jof10030215 

[12] Ziemlewska, A., Wójciak, M., Mroziak-Lal, K., Zagórska-Dziok, M., Bujak, T., Nizioł-Łukaszewska, Z., Szczepanek, D., & Sowa, I. (2022). Assessment of Cosmetic Properties and Safety of Use of Model Washing Gels with Reishi, Maitake and Lion's Mane Extracts. Molecules (Basel, Switzerland), 27(16), 5090. https://doi.org/10.3390/molecules27165090

[13] Matsuzaki, H., Shimizu, Y., Iwata, N., Kamiuchi, S., Suzuki, F., Iizuka, H., Hibino, Y., & Okazaki, M. (2013). Antidepressant-like effects of a water-soluble extract from the culture medium of Ganoderma lucidum mycelia in rats. BMC Complementary and Alternative Medicine, 13(1), 370. https://doi.org/10.1186/1472-6882-13-370 

[14] Socala, K., Nieoczym, D., Grzywnowicz, K., Stefaniuk, D., & Wlaz, P. (2015). Evaluation of Anticonvulsant, Antidepressant-, and Anxiolytic-like Effects of an Aqueous Extract from Cultured Mycelia of the Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Higher Basidiomycetes) in Mice. International journal of medicinal mushrooms, 17(3), 209–218. https://doi.org/10.1615/intjmedmushrooms.v17.i3.10 

[15] Cui, X., & Zhang, Y. (2019). Neuropharmacological Effect and Clinical Applications of Ganoderma (Lingzhi). Advances in experimental medicine and biology, 1182, 143–157. https://doi.org/10.1007/978-981-32-9421-9_5

[16] Dudhgaonkar, S., Thyagarajan, A., & Sliva, D. (2009). Suppression of the inflammatory response by triterpenes isolated from the mushroom Ganoderma lucidum. International immunopharmacology, 9(11), 1272–1280. https://doi.org/10.1016/j.intimp.2009.07.011 

[17] Vazirian, M., Faramarzi, M. A., Ebrahimi, S. E., Esfahani, H. R., Samadi, N., Hosseini, S. A., Asghari, A., Manayi, A., Mousazadeh, A., Asef, M. R., Habibi, E., & Amanzadeh, Y. (2014). Antimicrobial effect of the Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (higher Basidiomycetes) and its main compounds. International journal of medicinal mushrooms, 16(1), 77–84. https://doi.org/10.1615/intjmedmushr.v16.i1.70

[18] Chen, S., Chen, K., Lin, Y., Wang, S., Yu, H., Chang, C., Cheng, T., Hsieh, C., Li, J., Lai, H., Chen, D., & Huang, C. (2024). Ganoderic acid T, a Ganoderma triterpenoid, modulates the tumor microenvironment and enhances the chemotherapy and immunotherapy efficacy through downregulating galectin-1 levels. Toxicology and Applied Pharmacology, 491, 117069. https://doi.org/10.1016/j.taap.2024.117069